Research Institute for Bioscience and Biotechnology

Recent Updates
Dr. Paudel participated in a workshop on Current Trends in Chemical and Pharmaceutical Sciences, and Related Discipline, Phitsanulok Province, Thailand.                                                                                                                                                                                                           Dr. Bijay Singh participated in 27th TWAS General Meeting in Kigali, Rwanda                                                                                                                                                                                                           Dr. Bijay Singh wins Atta-ur-Rahman Prize 2016                                                                                                                                                                                                           Dr. Babita Paudel received Lunkaran Das Nawa Prativa (Emerging Talent) 2073                                                                                                                                                                                                           Dr. Sushila Maharjan participated in “TWAS Research Grants Conference – Shaping Careers in Science”                                                                                                                                                                                                           Dr. Paudel presented her work on Nepalese Lichens at Laos                                                                                                                                                                                                           Mr. Rajbhandari received travel award to participate in 2015 Food Biotechnology Training Course for Developing countries.                                                                                                                                                                                                           Dr. Maharjan awarded Elsevier Foundation Award 2016                                                                                                                                                                                                           Mr. Rajbhandari invited as guest of honor to attend International Energy Globe Award held in Tehran.                                                                                                                                                                                                           Dr. Bhattarai has been accepted for KOPRI Asian Polar Science Fellowship Program 2015.                                                                                                                                                                                                           President and Vice President presented in Asian Congress of Biotechnology (ACB – 2015).                                                                                                                                                                                                           Mr. Rajbhandari participated in international conference on organic farming (ICOF2015)                                                                                                                                                                                                           Mr. Rajbhandari participated in opening ceremony and workshop of KOICA-APP program                                                                                                                                                                                                           National Energy Globe Award 2015                                                                                                                                                                                                           Mr. Rajbhandari presented in seoul international conference on engineering and applied science (SICEAS-2015)                                                                                                                                                                                                           Mr. Shrestha presented at national conference on biotechnology                                                                                                                                                                                                           Dr. Bhattarai presented his research paper at national conference on biotechnology                                                                                                                                                                                                           Mr. Rajbhandari presented in TSB international forum                                                                                                                                                                                                           Prof. Lamichhane presented in TSB international forum                                                                                                                                                                                                           Mr. Rajbhandari presented at Mahidol University                                                                                                                                                                                                           Prof. Lamichhane presented at Mahidol University                                                                                                                                                                                                           “Nepal @ TOULOUSE”                                                                                                                                                                                                           MoU between RIBB and INP Toulouse                                                                                                                                                                                                           MoU between RIBB and iBR                                                                                                                                                                                                          

IFS Funded Research Projects

Project Title: Investigation of antimicrobial, anticancer and antioxidant secondary novel metabolites from lichens and their endophytes from high altitude regions of Nepal.

Link: http://ifs.se/

Project Introduction: Lichens are reported to be produced various biological active compounds. Lichens from extreme environments such as high altitude, high UV, drought and cold are believed to be synthesized unique types of secondary metabolites than the other one. Similarly, endophytic fungi or bacteria isolated from lichens from extreme environment are also believed to be produced unique and novel secondary metabolites in term of molecular structures and biological activities. Several human pathogenic bacteria and fungi have been deveoped into drug resistant strains. Various synthetic antioxidant compounds have posed carcinogenic effects. This phenomenon needs the further search for new effective drugs. 

The project aimed to investigate lichens and their endophytic fungi/bacteria from high altitude mountains of Nepal where such kind of research is yet to be carried out. During this research project, various lichens species from Annapurna Conservation Area (ACA) will be collected and endophytic fungi / bacteria will be isolated. All the organisms will be extracted with methanol and the extract will be screened for various biological activities such as antibacterial (against human pathogenic bacteria), antifungal (against pathogenic fungi), antioxidant and anticancer. Biological activity guided fractionation of the active extract will be carried out by using various chromatographic techniques such as column chromatography (silica gel), size exclusion chromatography (sephadex LH-20), thin layer chromatography, high performance liquid chromatography (HPLC). The purified active compounds will be identified by spectroscopic analysis such as ultraviolet, neuclear magnetic resonance (NMR) experiments. The obtained results will pave the way to conduct the further research of developing pharmaceutical or cosmetic drugs of natural origin to replace the existing synthetic compounds for better and safer applications.

Message From President

Welcome to the homepage of Research Institute for Bioscience and Biotechnology (RIBB). We are a young biotechnology based research institute thriving to work together with experts and young scientists of Nepal in the different field of biotechnology basically on Natural Products & Biodiversity, Pharmaceutical and Food Science and Bioenergy. Since our establishment in 2011, we have collaborated with scientists from around the world and within Nepal to provide a platform to conduct research of highest quality in Nepal.…

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